Do you want to analyze three-dimensional structures and highlight important features like active site residues, point mutations, and binding partners? Check out NCBI’s “I see in 3D” (iCn3D) – a free, web-based tool that allows you to explore the structure of a biomolecule at an atomistic level.
Features & Benefits
- Interactively view 3D structure and corresponding sequence data
- Align a protein sequence with unknown structure to a sequence-similar 3D structure
- Interactively view 3D alignments of similar structures
- View the interaction interfaces in a structure
- Save your custom display as a short URL or PNG image
- Share a link to your customized display of a structure
- Incorporate iCn3D into your own pages
Example
Figure: iCn3D display of an AlphaFold predicted structure for human catalase, as retrieved via its RefSeq protein accession. A conserved sequence feature is mapped to the structure and highlighted.
Check out our gallery with live examples.
Learn more
To learn more about iCn3D, read our help documentation or reference our workshop materials.
Questions?
Please reach out to us if you have questions or would like to provide feedback.
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