Do you work with or study prokaryotic proteins? As previously announced, we’ve been adding Gene Ontology (GO) terms to RefSeq prokaryotic protein sequence records (example below) to standardize the language when describing the functions of genes and their products. Over 100 million RefSeq proteins from prokaryotes now have at least one GO Term, a 55% increase since we started propagating GO terms from Conserved Domains Database (CDD) architectures in March.
Features & Benefits
GO terms allow you to quickly and easily:
- Understand the molecular function, biological processes, and cellular components associated with these proteins
- Compare proteins across different species and understand the functional relationships between different proteins within the same or different organisms
- Identify potential protein-protein interaction partners and metabolic pathways that involve these proteins
- Find proteins that contribute to cellular processes, such as metabolism, transport, and signaling
Example:
DNA polymerase IV [Syntrophomonas wolfei] 
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Questions?
If you have questions or would like to provide feedback, please reach out to us at info@ncbi.nlm.nih.gov.