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Eman Ali

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Poonooru Ravikanth Reddy

Sri Venkateswara Veterinary University

Adegbola Adesogan

North Carolina State University

erastus Kangethe

Szilveszter Csorba

Christine Burel

Shahida Anusha Siddiqui

Universidad Nacional de Asuncion

Everton Luis Krabbe

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Papers by Eman Ali

Evaluation of the Adsorption Efficacy of Bentonite on Aflatoxin M1 Levels in Contaminated Milk

Toxins

The existence of aflatoxin M1 (AFM1) in raw milk results in economic losses and public health ris... more The existence of aflatoxin M1 (AFM1) in raw milk results in economic losses and public health risks. This research aims to examine the capability of bentonite to adsorb and/or eliminate AFM1 from various raw milk types. In addition, the effects of numerous bentonites (HAFR 1, 2, 3 and 4) on the nutritional characteristics of the milk were studied. Our findings revealed that goat milk had the highest value of AFM1 (490.30 ng/L) in comparison to other milks. AFM1 adsorption was influenced by applying bentonite (0.5 and 1 g) in a concentration-dependent manner for different time intervals (from 0 to 12 h). The percentage of AFM1 reached the maximum adsorption level after 12 h to 100, 98.5 and 98% for bentonites HAFR 3, 1 and 2, respectively. HAFR 3 (1 g bentonite) presented higher adsorption efficiency than other bentonites used in the phosphate buffer saline (PBS) and milk. Residual levels of AFM1 reached their lowest values of 0 and 1.5 ng/L while using HAFR 3 in PBS and milk, respec...

Urban flooding and risk of leptospirosis; Pakistan on the verge of a new disaster: A call for action

International Journal of Hygiene and Environmental Health

Association of HLA Class I and II Antigens with Vitiligo in Egyptian Population

Molecular Enzymology and Drug Targets

The association of HLA antigens with vitiligo remains controversial issue. In order to determine ... more The association of HLA antigens with vitiligo remains controversial issue. In order to determine which, if any, HLA markers were associated with an increased risk of vitiligo, we investigated HLA antigens in 50 patients with vitiligo and in 50 controls. Vitiligo patients had significant increase in HLA-A1, A19, B16, CW4, CW 6, DR 4, DR7 and DQ3 compared to controls. Familial vitiligo is marked by increased frequency of HLA-A28, B16, B27, B48, CW2 and DQ3, while non-familial vitiligo is marked by increased frequency of HLA-A1, CW6 and DR13. These findings suggest that immunogenetic mechanism may be responsible for vitiligo. Also there may be heterogeneity in the pathogenic process between familial and nonfamilial vitiligo. Keywords HLA Class I and II antigens; Vitiligo; Egypt II-Control group The control group was composed of 50 healthy blood donors coming to Benha University Hospital. There were 32 males and 18 females with age ranging from 10 to 50 years (mean=31.3).

Level of Stress Among Pregnant Women with Heart Problems

International Journal of Research -GRANTHAALAYAH, 2016

Although its prevalence is comparatively low in pregnant women, heart disease is the most signifi... more Although its prevalence is comparatively low in pregnant women, heart disease is the most significant cause of maternal mortality. About 2% of pregnancies involve maternal cardiovascular disease and this poses an increased risk to both mother and fetus. In-depth interviews for the convenience of 178 pregnant women with heart disease going through 400 pregnancies associated with medical disorders, which were booked in the high-risk obstetric departments and the antenatal outpatient clinics at all governmental hospitals in Beni-Surf City. The prevalence of heart disease of Pregnancy was 44.5%. The severity level of stress was found in the age group of 25-30 years, obese women, urban areas and women who were in their first trimester, Multigravida and who had a history still birth/birth defects. Statistically significant correlation was found between stress levels and age, education, occupation, income, obesity and residence. There is substantial evidence that heart disease with pregnan...

An Advanced Automatic Fuzzy Rule-Based Algorithm for 3D Vessel Segmentation

International Journal of Computational Intelligence Systems, 2018

Fuzzy Logic has played an important role in medical image (MI) segmentation in the last decade. A... more Fuzzy Logic has played an important role in medical image (MI) segmentation in the last decade. Automatic blood vessel segmentation from 3D medical images is an emerging area where segmentation algorithms could be combined with evolutionary computation methods for better diagnosis and higher decision accuracy. This paper introduces an automatic blood vessel segmentation algorithm from 3D images using Fuzzy logic. The proposed fuzzy system decides degree of Vesselness according to Eigen values of Hessian matrix. 3D synthetic and real CTA clinical image database are used to test the proposed algorithm and show a correct voxel classification. The proposed method shows better segmentation results compared to manual and swarm intelligence methods. Furthermore, fuzzy has led to better time improvement.

Multifocal objective pupil perimetry in migraine

Investigative Ophthalmology & Visual Science, 2016

Ultrastructural Features of the Human Mammary Gland Carcinomas

Ultrastructural Features of the Human Mammary Gland Carcinomas، للحصول على النص الكامل يرجى زيارة... more

The Relationship Between Emotional Intelligence and Transformational Leadership Style of Managers as Perceived by Their Employees

The Relationship Between Emotional Intelligence and Transformational Leadership Style of Managers... more The Relationship Between Emotional Intelligence and Transformational Leadership Style of Managers as Perceived by Their Employees، للحصول على النص الكامل يرجى زيارة مكتبة الحسين بن طلال في جامعة اليرموك او زيارة موقعها الالكتروني

Investigation of allergenicity of Schistosoma mansoni antigens using RS-ATL8 reporter cell line assay

Human schistosomiasis is one of the helminthic neglected tropical diseases. It leads to serious h... more Human schistosomiasis is one of the helminthic neglected tropical diseases. It leads to serious health problems and imposes a huge burden on communities. All interactions between the parasite and the human body occur at a molecular and cellular level. Therefore, the study of the molecular aspects of infection and the immune response is a very active area of research. It has been known for decades that there is a direct relationship between protection against infection, or reinfection after treatment, and parasite-specific Immunoglobulin E (IgE) antibody in infected individuals. This study aims to investigate the allergenicity of S. mansoni antigens using RS-ATL8 reporter cell line assay. Towards this goal, I first identified the best reporter cell line for allergenicity assessment. This was done by the characterisation of the transgenic human FcԑRIα chain’s gene copy number and by comparing the levels of human FcԑRI receptor surface expression. The second goal was the optimisation o...

47. Effects of stimulating melanopsin-containing retinal ganglion cells in migraine patients using multifocal objective pupillometry

Journal of Clinical Neuroscience, 2014

Recent evidence has linked intrinsically-photosensitive retinal ganglion cells (ipRGC) to photose... more Recent evidence has linked intrinsically-photosensitive retinal ganglion cells (ipRGC) to photosensitivity in migraine. It is possible that multifocal pupillographic objective perimetry (mfPOP) might exacerbate migraine and the response to mfPOP might be different in migraineurs. This study aimed to establish the effects of stimulating ipRGC using mfPOP on migraine severity parameters and pupillary response characteristics. A randomized case-control crossover study tested migraineurs and normal controls using mfPOP utilising a blue protocol to target the intrinsic melanopsin response of the ipRGC and a yellow protocol to stimulate cone photoreceptors. Migraine diaries were obtained a week prior to and a week after each testing. Responses were analysed according to response time-to-peak and standardised amplitude (AmpStd). The percentage area under the receiver operator characteristic curve (%AUC) was used to predict migraine status. Thirty-eight migraineurs and 24 normal controls we...

Towards A Global Cosmic Ray Sensor Network: CREDO Detector as the First Open-Source Mobile Application Enabling Detection of Penetrating Radiation

Symmetry, 2020

We present the purpose, long-term development vision, basic design, detection algorithm and preli... more We present the purpose, long-term development vision, basic design, detection algorithm and preliminary results obtained with the Cosmic Ray Extremely Distributed Observatory (CREDO) Detector mobile application. The CREDO Detector app and related infrastructure are unique in terms of their scale, targeting many form-factors and open-access philosophy. This philosophy translates to the open-source code of the app, open-access in terms of both data inflow as well as data consumption and above all, the citizen science philosophy that means that the infrastructure is open to all who wish to participate in the project. The CREDO infrastructure and CREDO Detector app are designed for the large-scale study of various radiation forms that continuously reach the Earth from space, but with the sensitivity to local radioactivity as well. Such study has great significance both scientifically and educationally as cosmic radiation has an impact on diverse research areas from life on Earth to the ...

The Association Between Clinicopathological Features and Molecular Markers in Bahraini Women With Breast Cancer

The Gulf journal of oncology, 2020

INTRODUCTION Breast cancer (BC) is a heterogenous disease and a major public health burden in Bah... more INTRODUCTION Breast cancer (BC) is a heterogenous disease and a major public health burden in Bahrain. Based on hormone receptor status (ER, PR, and HER2), BC can be divided into four molecular subtypes: Luminal A, Luminal B, HER2+, and Triple negative, each of which display distinct clinical behaviour. PATIENTS AND METHODS This retrospective study included 216 patients diagnosed with BC between November 2017 and May 2019 at the Bahrain oncology centre. The clinicopathological characteristics (age, size of tumour, grade, lymph node involvement, metastasis) were examined, in addition to immunohistochemical markers (ER, PR, and HER2), and BRCA 1 and 2 status (when indicated). SPSS was used to evaluate the correlation between the molecular subtypes and different clinicopathological features. RESULTS BC in Bahraini women was relatively of large size (68.5% larger than 20mm), with frequent metastasis to the lymph nodes (57.4%). The mean age at diagnosis was 51.8 years ±11.5, with invasiv...

Quality of Smoked Tilapia Fillets (Oreochromis niloticus) Treated by Traditional and Liquid Smoke

Aquatic Science and Fish Resources (ASFR), 2021

The purpose of this study was to treat tilapia fillets by traditional smoke (hot and cold smoking... more The purpose of this study was to treat tilapia fillets by traditional smoke (hot and cold smoking) and liquid smoke (watery smoke and oily smoke), and examined the effects of these treatments on the fillets quality. The proximate composition and nutritional values were determined. The cold smoked fillets had the highest percentage, 43.97%; 8.3%; 6.05% and 274.78 Kcal, of protein, fat, carbohydrates and nutritional value, respectively. Salt percentage was less than 3.5% in all smoked tilapia fillets treatments and compiled with EOS standards (2005). TVB-N and TBA values were lower (<25mg/ 100g; <1.5mg Malondialdehyde/ kg) in all smoked tilapia fillets. TPC and Yeasts and molds counts ranged between 2.54×102 and 2.49×103 cfu/g; 1.26×102 and 0.23×102 cfu/g, in all smoked tilapia fillets treatments respectively, were complied with EOS standards. The organoleptic properties showed excellent and very good scores for traditional and liquid smoking fillets, respectively. Smoked tilapia fillets (Oreochromis niloticus) treated by Liquid Smoke can be considered a good alternative to traditional smoking.

Biodistribltion of Labeled IOD0-AZATHIOPRINE in Eac Tumor Bearing Mice

Zagazig Journal of Pharmaceutical Sciences, 2007

Evaluation of Alveolar Ridge Preservation Using a composite of Bioactive Glass and Platelet Rich Fibrin Alone or Combined with Melatonin in Chronic Periodontitis Patient

Al-Azhar Dental Journal for Girls, 2018

Purpose: The aim of this randomized controlled clinical trial was the evaluation of alveolar ridg... more Purpose: The aim of this randomized controlled clinical trial was the evaluation of alveolar ridge preservation using a composite of bioactive glass and platelet rich fibrin either alone or combined with melatonin in chronic periodontitis patients. This aim was fulfilled through: Clinical assessment and radiographic assessment. Subjects and Methods: A total of thirty extraction sockets in 29 patients were randomly divided into three groups; control group treated by atraumatic extraction alone, test1 group (application of bioactive glass mixed with PRF) and test 2 group (application of bioactive glass mixed with PRF and melatonin gel). The clinical parameters recorded at baseline, 3 months and 6 months after treatment. Cone beam tomography radiographs used to measure width of socket at base line and 6months post operatively. Results: By clinical assessment both group II and group III showed significant increase in length and width of alveolar ridge with significant difference between the two groups in the whole study period. Radiographically; both group II and group III showed a significant increase in all parameters by time, while control group, there was a significant decrease at the end of the study period. Conclusion: Within the limits of this study: The composite use of bioglass, Prf & melatonin in group III reflected the best clinical, and radiographic results.

Antimicrobial Activity of Terpenoids Extracted from Annona muricata Seeds and its Endophytic Aspergillus niger Strain SH3 Either Singly or in Combination

Open Access Macedonian Journal of Medical Sciences, 2019

BACKGROUND: Annona muricata (Soursop) has an antimicrobial activity toward various pathogenic mic... more BACKGROUND: Annona muricata (Soursop) has an antimicrobial activity toward various pathogenic microorganisms which support its ethnomedicinal for the treatment of many infectious diseases. AIM: Aim of the present study to evaluate the relation between antimicrobial activities of terpenoids extracted from different soursop parts with the isolated endophytic fungi. METHODS: Endophytic fungal species of pulp and peel of Annona fruit along with those of seeds were isolated. Salkowski test was used for qualitative screening of terpenoids in plant and the isolated endophytic Aspergillus niger strain SH3. RESULTS: Endophytic A. niger strain SH3 and Annona seed extract showed high terpenoid content indicated by the high intensity of reddish-brown colour. GC/Mass analysis revealed six compounds of terpenoids from endophytic A. niger strain SH3 extract and four compounds from seed extract with different retention times. The antimicrobial assay was performed using A. niger strain SH3 extract a...

Use of Mass Spectrometry to Profile Peptides in Whey Protein Isolate Medium Fermented by Lactobacillus helveticus LH-2 and Lactobacillus acidophilus La-5

Frontiers in Nutrition, 2019

Peptides in the 3-kDa ultrafiltrate of fermented whey protein isolate (WPI) medium could be respo... more Peptides in the 3-kDa ultrafiltrate of fermented whey protein isolate (WPI) medium could be responsible for the antivirulence activity of Lactobacillus helveticus LH-2 and Lactobacillus acidophilus La-5 against Salmonella Typhimurium. Non-fermented and fermented media containing 5.6% WPI were fractionated at a 3 kDa cutoff and the filtrate was analyzed by mass spectrometry. The non-fermented WPI medium contained 109 milk derived peptides, which originated from β-casein (52), αs1-casein (22), αs2-casein (10), κ-casein (8), and β-lactoglobulin (17). Most of these peptides were not found in the fermented media, except for 14 peptides from β-casein and one peptide from α s2-casein. Database searches confirmed that 39 out of the 109 peptides had established physiological functions, including angiotensin-converting-enzyme (ACE) inhibitory, antioxidant, antimicrobial, or immunomodulating activity. A total of 75 peptides were found in the LH-2 cell free spent medium (CFSM): 54 from β-casein, 14 from k-casein, 4 from β-lactoglobulin and 3 from αs2-casein. From these peptides, 19 have previously been associated with several categories of bioactivity. For La-5 CFSM, a total of 15 peptides were sequenced: 8 from β-casein, 5 from αs1-casein, 2 from β-lactoglobulin. Only 5 of these have previously been reported as having bioactivity. Many of the peptides remaining in the fermented medium would contain low-affinity residues for oligopeptide binding proteins and higher resistance to peptidase hydrolysis. These properties of the sequenced peptides could explain their accumulation after fermentation despite the active proteolytic enzymes of LH-2 and La-5 strains. Down-regulated expression of hilA and ssrB genes in S. Typhimurium was observed in the presence of La-5 and LH-2 CFSM. Downregulation was not observed for the Salmonella oppA mutant strain exposed to the same CFSM used to treat the S. Typhimurium DT104 wild-type strain. This result suggests the importance of peptide transport by S. Typhimurium for down regulation of virulence genes in Salmonella.

Screening of Antibacterial Activity In Vitro ofEryngium creticum

Research Journal of Pharmacy and Technology, 2016

This study is conducted to evaluate the antimicrobial activity of one extract of Styrax officinal... more This study is conducted to evaluate the antimicrobial activity of one extract of Styrax officinalis L envelopes of berries plant belonging to the Styracae family collected from the coastal area surrounding the city of Lattakia, Syria. Many efforts have been made to discover a new antimicrobial from a variety of sources such as microorganisms, animals and plants. One such source is Folk medicine. Systematic screening of them may result in the discovery of a new effective compound. These extracts are prepared with polar solvent (methanol) by the steeping extraction method. The antimicrobial activity of the extracts is then assessed using the disk diffusion method against gram-positive (Staphylococcus aureus), and gram-negative (Escherichia coli) bacteria. The methanolic extracts of Styrax officinalis L envelopes of berries have shown antimicrobial activities against the tested bacteria. The activity is compared with potent broad spectrum antibiotics such as Cefipime, Amikacine and Ceftriaxon.

Degradation of engraved stone and renders from Qasr Qarun Temple in Fayoum Oasis, Egypt

ABSTRACT

MESP: A Modified IPSec for Secure Multicast Communication

2006 6th International Conference on ITS Telecommunications, 2006

Page 1. 2006 6th Intermational Coference on ITS Teleconuiiic&amp;amp;ations Proceedings MESP:... more

Evaluation of the Adsorption Efficacy of Bentonite on Aflatoxin M1 Levels in Contaminated Milk

Toxins

The existence of aflatoxin M1 (AFM1) in raw milk results in economic losses and public health ris... more The existence of aflatoxin M1 (AFM1) in raw milk results in economic losses and public health risks. This research aims to examine the capability of bentonite to adsorb and/or eliminate AFM1 from various raw milk types. In addition, the effects of numerous bentonites (HAFR 1, 2, 3 and 4) on the nutritional characteristics of the milk were studied. Our findings revealed that goat milk had the highest value of AFM1 (490.30 ng/L) in comparison to other milks. AFM1 adsorption was influenced by applying bentonite (0.5 and 1 g) in a concentration-dependent manner for different time intervals (from 0 to 12 h). The percentage of AFM1 reached the maximum adsorption level after 12 h to 100, 98.5 and 98% for bentonites HAFR 3, 1 and 2, respectively. HAFR 3 (1 g bentonite) presented higher adsorption efficiency than other bentonites used in the phosphate buffer saline (PBS) and milk. Residual levels of AFM1 reached their lowest values of 0 and 1.5 ng/L while using HAFR 3 in PBS and milk, respec...

Urban flooding and risk of leptospirosis; Pakistan on the verge of a new disaster: A call for action

International Journal of Hygiene and Environmental Health

Association of HLA Class I and II Antigens with Vitiligo in Egyptian Population

Molecular Enzymology and Drug Targets

The association of HLA antigens with vitiligo remains controversial issue. In order to determine ... more The association of HLA antigens with vitiligo remains controversial issue. In order to determine which, if any, HLA markers were associated with an increased risk of vitiligo, we investigated HLA antigens in 50 patients with vitiligo and in 50 controls. Vitiligo patients had significant increase in HLA-A1, A19, B16, CW4, CW 6, DR 4, DR7 and DQ3 compared to controls. Familial vitiligo is marked by increased frequency of HLA-A28, B16, B27, B48, CW2 and DQ3, while non-familial vitiligo is marked by increased frequency of HLA-A1, CW6 and DR13. These findings suggest that immunogenetic mechanism may be responsible for vitiligo. Also there may be heterogeneity in the pathogenic process between familial and nonfamilial vitiligo. Keywords HLA Class I and II antigens; Vitiligo; Egypt II-Control group The control group was composed of 50 healthy blood donors coming to Benha University Hospital. There were 32 males and 18 females with age ranging from 10 to 50 years (mean=31.3).

Level of Stress Among Pregnant Women with Heart Problems

International Journal of Research -GRANTHAALAYAH, 2016

Although its prevalence is comparatively low in pregnant women, heart disease is the most signifi... more Although its prevalence is comparatively low in pregnant women, heart disease is the most significant cause of maternal mortality. About 2% of pregnancies involve maternal cardiovascular disease and this poses an increased risk to both mother and fetus. In-depth interviews for the convenience of 178 pregnant women with heart disease going through 400 pregnancies associated with medical disorders, which were booked in the high-risk obstetric departments and the antenatal outpatient clinics at all governmental hospitals in Beni-Surf City. The prevalence of heart disease of Pregnancy was 44.5%. The severity level of stress was found in the age group of 25-30 years, obese women, urban areas and women who were in their first trimester, Multigravida and who had a history still birth/birth defects. Statistically significant correlation was found between stress levels and age, education, occupation, income, obesity and residence. There is substantial evidence that heart disease with pregnan...

An Advanced Automatic Fuzzy Rule-Based Algorithm for 3D Vessel Segmentation

International Journal of Computational Intelligence Systems, 2018

Fuzzy Logic has played an important role in medical image (MI) segmentation in the last decade. A... more Fuzzy Logic has played an important role in medical image (MI) segmentation in the last decade. Automatic blood vessel segmentation from 3D medical images is an emerging area where segmentation algorithms could be combined with evolutionary computation methods for better diagnosis and higher decision accuracy. This paper introduces an automatic blood vessel segmentation algorithm from 3D images using Fuzzy logic. The proposed fuzzy system decides degree of Vesselness according to Eigen values of Hessian matrix. 3D synthetic and real CTA clinical image database are used to test the proposed algorithm and show a correct voxel classification. The proposed method shows better segmentation results compared to manual and swarm intelligence methods. Furthermore, fuzzy has led to better time improvement.

Multifocal objective pupil perimetry in migraine

Investigative Ophthalmology & Visual Science, 2016

Ultrastructural Features of the Human Mammary Gland Carcinomas

Ultrastructural Features of the Human Mammary Gland Carcinomas، للحصول على النص الكامل يرجى زيارة... more

The Relationship Between Emotional Intelligence and Transformational Leadership Style of Managers as Perceived by Their Employees

The Relationship Between Emotional Intelligence and Transformational Leadership Style of Managers... more The Relationship Between Emotional Intelligence and Transformational Leadership Style of Managers as Perceived by Their Employees، للحصول على النص الكامل يرجى زيارة مكتبة الحسين بن طلال في جامعة اليرموك او زيارة موقعها الالكتروني

Investigation of allergenicity of Schistosoma mansoni antigens using RS-ATL8 reporter cell line assay

Human schistosomiasis is one of the helminthic neglected tropical diseases. It leads to serious h... more Human schistosomiasis is one of the helminthic neglected tropical diseases. It leads to serious health problems and imposes a huge burden on communities. All interactions between the parasite and the human body occur at a molecular and cellular level. Therefore, the study of the molecular aspects of infection and the immune response is a very active area of research. It has been known for decades that there is a direct relationship between protection against infection, or reinfection after treatment, and parasite-specific Immunoglobulin E (IgE) antibody in infected individuals. This study aims to investigate the allergenicity of S. mansoni antigens using RS-ATL8 reporter cell line assay. Towards this goal, I first identified the best reporter cell line for allergenicity assessment. This was done by the characterisation of the transgenic human FcԑRIα chain’s gene copy number and by comparing the levels of human FcԑRI receptor surface expression. The second goal was the optimisation o...

47. Effects of stimulating melanopsin-containing retinal ganglion cells in migraine patients using multifocal objective pupillometry

Journal of Clinical Neuroscience, 2014

Recent evidence has linked intrinsically-photosensitive retinal ganglion cells (ipRGC) to photose... more Recent evidence has linked intrinsically-photosensitive retinal ganglion cells (ipRGC) to photosensitivity in migraine. It is possible that multifocal pupillographic objective perimetry (mfPOP) might exacerbate migraine and the response to mfPOP might be different in migraineurs. This study aimed to establish the effects of stimulating ipRGC using mfPOP on migraine severity parameters and pupillary response characteristics. A randomized case-control crossover study tested migraineurs and normal controls using mfPOP utilising a blue protocol to target the intrinsic melanopsin response of the ipRGC and a yellow protocol to stimulate cone photoreceptors. Migraine diaries were obtained a week prior to and a week after each testing. Responses were analysed according to response time-to-peak and standardised amplitude (AmpStd). The percentage area under the receiver operator characteristic curve (%AUC) was used to predict migraine status. Thirty-eight migraineurs and 24 normal controls we...

Towards A Global Cosmic Ray Sensor Network: CREDO Detector as the First Open-Source Mobile Application Enabling Detection of Penetrating Radiation

Symmetry, 2020

We present the purpose, long-term development vision, basic design, detection algorithm and preli... more We present the purpose, long-term development vision, basic design, detection algorithm and preliminary results obtained with the Cosmic Ray Extremely Distributed Observatory (CREDO) Detector mobile application. The CREDO Detector app and related infrastructure are unique in terms of their scale, targeting many form-factors and open-access philosophy. This philosophy translates to the open-source code of the app, open-access in terms of both data inflow as well as data consumption and above all, the citizen science philosophy that means that the infrastructure is open to all who wish to participate in the project. The CREDO infrastructure and CREDO Detector app are designed for the large-scale study of various radiation forms that continuously reach the Earth from space, but with the sensitivity to local radioactivity as well. Such study has great significance both scientifically and educationally as cosmic radiation has an impact on diverse research areas from life on Earth to the ...

The Association Between Clinicopathological Features and Molecular Markers in Bahraini Women With Breast Cancer

The Gulf journal of oncology, 2020

INTRODUCTION Breast cancer (BC) is a heterogenous disease and a major public health burden in Bah... more INTRODUCTION Breast cancer (BC) is a heterogenous disease and a major public health burden in Bahrain. Based on hormone receptor status (ER, PR, and HER2), BC can be divided into four molecular subtypes: Luminal A, Luminal B, HER2+, and Triple negative, each of which display distinct clinical behaviour. PATIENTS AND METHODS This retrospective study included 216 patients diagnosed with BC between November 2017 and May 2019 at the Bahrain oncology centre. The clinicopathological characteristics (age, size of tumour, grade, lymph node involvement, metastasis) were examined, in addition to immunohistochemical markers (ER, PR, and HER2), and BRCA 1 and 2 status (when indicated). SPSS was used to evaluate the correlation between the molecular subtypes and different clinicopathological features. RESULTS BC in Bahraini women was relatively of large size (68.5% larger than 20mm), with frequent metastasis to the lymph nodes (57.4%). The mean age at diagnosis was 51.8 years ±11.5, with invasiv...

Quality of Smoked Tilapia Fillets (Oreochromis niloticus) Treated by Traditional and Liquid Smoke

Aquatic Science and Fish Resources (ASFR), 2021

The purpose of this study was to treat tilapia fillets by traditional smoke (hot and cold smoking... more The purpose of this study was to treat tilapia fillets by traditional smoke (hot and cold smoking) and liquid smoke (watery smoke and oily smoke), and examined the effects of these treatments on the fillets quality. The proximate composition and nutritional values were determined. The cold smoked fillets had the highest percentage, 43.97%; 8.3%; 6.05% and 274.78 Kcal, of protein, fat, carbohydrates and nutritional value, respectively. Salt percentage was less than 3.5% in all smoked tilapia fillets treatments and compiled with EOS standards (2005). TVB-N and TBA values were lower (<25mg/ 100g; <1.5mg Malondialdehyde/ kg) in all smoked tilapia fillets. TPC and Yeasts and molds counts ranged between 2.54×102 and 2.49×103 cfu/g; 1.26×102 and 0.23×102 cfu/g, in all smoked tilapia fillets treatments respectively, were complied with EOS standards. The organoleptic properties showed excellent and very good scores for traditional and liquid smoking fillets, respectively. Smoked tilapia fillets (Oreochromis niloticus) treated by Liquid Smoke can be considered a good alternative to traditional smoking.

Biodistribltion of Labeled IOD0-AZATHIOPRINE in Eac Tumor Bearing Mice

Zagazig Journal of Pharmaceutical Sciences, 2007

Evaluation of Alveolar Ridge Preservation Using a composite of Bioactive Glass and Platelet Rich Fibrin Alone or Combined with Melatonin in Chronic Periodontitis Patient

Al-Azhar Dental Journal for Girls, 2018

Purpose: The aim of this randomized controlled clinical trial was the evaluation of alveolar ridg... more Purpose: The aim of this randomized controlled clinical trial was the evaluation of alveolar ridge preservation using a composite of bioactive glass and platelet rich fibrin either alone or combined with melatonin in chronic periodontitis patients. This aim was fulfilled through: Clinical assessment and radiographic assessment. Subjects and Methods: A total of thirty extraction sockets in 29 patients were randomly divided into three groups; control group treated by atraumatic extraction alone, test1 group (application of bioactive glass mixed with PRF) and test 2 group (application of bioactive glass mixed with PRF and melatonin gel). The clinical parameters recorded at baseline, 3 months and 6 months after treatment. Cone beam tomography radiographs used to measure width of socket at base line and 6months post operatively. Results: By clinical assessment both group II and group III showed significant increase in length and width of alveolar ridge with significant difference between the two groups in the whole study period. Radiographically; both group II and group III showed a significant increase in all parameters by time, while control group, there was a significant decrease at the end of the study period. Conclusion: Within the limits of this study: The composite use of bioglass, Prf & melatonin in group III reflected the best clinical, and radiographic results.

Antimicrobial Activity of Terpenoids Extracted from Annona muricata Seeds and its Endophytic Aspergillus niger Strain SH3 Either Singly or in Combination

Open Access Macedonian Journal of Medical Sciences, 2019

BACKGROUND: Annona muricata (Soursop) has an antimicrobial activity toward various pathogenic mic... more BACKGROUND: Annona muricata (Soursop) has an antimicrobial activity toward various pathogenic microorganisms which support its ethnomedicinal for the treatment of many infectious diseases. AIM: Aim of the present study to evaluate the relation between antimicrobial activities of terpenoids extracted from different soursop parts with the isolated endophytic fungi. METHODS: Endophytic fungal species of pulp and peel of Annona fruit along with those of seeds were isolated. Salkowski test was used for qualitative screening of terpenoids in plant and the isolated endophytic Aspergillus niger strain SH3. RESULTS: Endophytic A. niger strain SH3 and Annona seed extract showed high terpenoid content indicated by the high intensity of reddish-brown colour. GC/Mass analysis revealed six compounds of terpenoids from endophytic A. niger strain SH3 extract and four compounds from seed extract with different retention times. The antimicrobial assay was performed using A. niger strain SH3 extract a...

Use of Mass Spectrometry to Profile Peptides in Whey Protein Isolate Medium Fermented by Lactobacillus helveticus LH-2 and Lactobacillus acidophilus La-5

Frontiers in Nutrition, 2019

Peptides in the 3-kDa ultrafiltrate of fermented whey protein isolate (WPI) medium could be respo... more Peptides in the 3-kDa ultrafiltrate of fermented whey protein isolate (WPI) medium could be responsible for the antivirulence activity of Lactobacillus helveticus LH-2 and Lactobacillus acidophilus La-5 against Salmonella Typhimurium. Non-fermented and fermented media containing 5.6% WPI were fractionated at a 3 kDa cutoff and the filtrate was analyzed by mass spectrometry. The non-fermented WPI medium contained 109 milk derived peptides, which originated from β-casein (52), αs1-casein (22), αs2-casein (10), κ-casein (8), and β-lactoglobulin (17). Most of these peptides were not found in the fermented media, except for 14 peptides from β-casein and one peptide from α s2-casein. Database searches confirmed that 39 out of the 109 peptides had established physiological functions, including angiotensin-converting-enzyme (ACE) inhibitory, antioxidant, antimicrobial, or immunomodulating activity. A total of 75 peptides were found in the LH-2 cell free spent medium (CFSM): 54 from β-casein, 14 from k-casein, 4 from β-lactoglobulin and 3 from αs2-casein. From these peptides, 19 have previously been associated with several categories of bioactivity. For La-5 CFSM, a total of 15 peptides were sequenced: 8 from β-casein, 5 from αs1-casein, 2 from β-lactoglobulin. Only 5 of these have previously been reported as having bioactivity. Many of the peptides remaining in the fermented medium would contain low-affinity residues for oligopeptide binding proteins and higher resistance to peptidase hydrolysis. These properties of the sequenced peptides could explain their accumulation after fermentation despite the active proteolytic enzymes of LH-2 and La-5 strains. Down-regulated expression of hilA and ssrB genes in S. Typhimurium was observed in the presence of La-5 and LH-2 CFSM. Downregulation was not observed for the Salmonella oppA mutant strain exposed to the same CFSM used to treat the S. Typhimurium DT104 wild-type strain. This result suggests the importance of peptide transport by S. Typhimurium for down regulation of virulence genes in Salmonella.

Screening of Antibacterial Activity In Vitro ofEryngium creticum

Research Journal of Pharmacy and Technology, 2016

This study is conducted to evaluate the antimicrobial activity of one extract of Styrax officinal... more This study is conducted to evaluate the antimicrobial activity of one extract of Styrax officinalis L envelopes of berries plant belonging to the Styracae family collected from the coastal area surrounding the city of Lattakia, Syria. Many efforts have been made to discover a new antimicrobial from a variety of sources such as microorganisms, animals and plants. One such source is Folk medicine. Systematic screening of them may result in the discovery of a new effective compound. These extracts are prepared with polar solvent (methanol) by the steeping extraction method. The antimicrobial activity of the extracts is then assessed using the disk diffusion method against gram-positive (Staphylococcus aureus), and gram-negative (Escherichia coli) bacteria. The methanolic extracts of Styrax officinalis L envelopes of berries have shown antimicrobial activities against the tested bacteria. The activity is compared with potent broad spectrum antibiotics such as Cefipime, Amikacine and Ceftriaxon.

Degradation of engraved stone and renders from Qasr Qarun Temple in Fayoum Oasis, Egypt

ABSTRACT

MESP: A Modified IPSec for Secure Multicast Communication

2006 6th International Conference on ITS Telecommunications, 2006

Page 1. 2006 6th Intermational Coference on ITS Teleconuiiic&amp;amp;ations Proceedings MESP:... more