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Cebrail Kisa

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University of Galway

University of Alabama - Tuscaloosa

Martin van Bruinessen

Universiteit Utrecht

University of Trento

Ozyegin University

Leonidas Cheliotis

London School of Economics and Political Science

Dan Rodríguez-García

Universitat Autònoma de Barcelona

Durham University

Stephan Dünnwald

ISCTE - University Institute of Lisbon (ISCTE-IUL)

Alina Rzepnikowska

The University of Manchester

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Papers by Cebrail Kisa

A comparison of symptom dimensions for obsessive compulsive disorder and obsessive compulsive-related disorders

PLOS ONE, 2019

In this study, it is aimed to determine obsessive compulsive-related disorders (OCRDs) comorbidit... more In this study, it is aimed to determine obsessive compulsive-related disorders (OCRDs) comorbidity among the patients with obsessive compulsive disorder (OCD) and compare patients with OCD with or without comorbid OCRDs in terms of the severity of their OCD symptoms, symptom dimensions, and comorbidity with other axis I disorders. The study included 90 patients diagnosed as having OCD according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR). The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) diagnostic criteria for OCRDs were used to determine the presence of OCRDs. In order to determine the symptom dimensions and severity of these individuals' OCD symptoms, we administered the Dimensional Obsessive Compulsive Scale (DOCS) and The Yale-Brown Obsessive Compulsive Scale (Y-BOCS). In our study, 20% of the patients with OCD simultaneously met the criteria for at least one OCRD, we also found that a significantly greater proportion of this group were men. None of the mentioned disorders was associated with any symptom dimensions we evaluated using DOCS. In addition, no differences were found in the severity of OCD symptoms and comorbid axis I disorders between the group with comorbid OCRDs and the group without comorbid OCRDs. There was no significant relationship between the symptom dimensions of OCD and OCRDs. It is found that OCRD comorbidity does not increase the severity of OCD symptoms and the prevalence of an axis I diagnosis.

Farkli Kategori̇de Yarişan Taekwondocularin Spor Yaralanmalarina Karşi, Kaygi Durumlarinin İncelenmesi̇

The Online Journal of Recreation and Sport

This study aims to examine the sports injury anxiety levels of taekwondo players, which is a psyc... more This study aims to examine the sports injury anxiety levels of taekwondo players, which is a psychological factor that causes injury and negatively affects athletes apart from some physical strategies in the prevention of injuries. A total of 617 (326 men and 291 women) taekwondo players actively engaged in sports from different competition categories participated in the study.

Karbamazepin Tedavisi Sırasında Gelişen Hiponatremi Ve Sonuçları: Bir Olgu Sunumu

Klozapin tedavisini pimozid ile güçlendirme yaklaşımı: Tedaviye dirençli bir şizofreni olgusu

Noropsikiyatri Arsivi-archives of Neuropsychiatry, 2010

Page 1. Hatice ALKAN AKDA⁄, Cebrail KISA, Gülcan BEKK‹, Erol GÖKA Numune Hastanesi 1. Psikiyatri ... more

The effects of prolactin-raising and prolactin-sparing antipsychotics on prolactin levels and bone mineral density in schizophrenic patients/Sizofreni tanili hastalarda prolaktini yukselten ve az etkileyen antipsikotiklerin prolaktin seviyesi ve kemik mineral yogunlugu uzerine etkileri

Archives of Neuropsychiatry, Sep 1, 2014

Hekimlerin Konversiyon Bozukluğuna Yaklaşımını Etkileyen Faktörler

Klinik Psikiyatri …, 2004

Page 1. Hekimlerin Konversiyon Bozukluğuna Yaklaşımını Etkileyen Faktörler Uğur Bediz1, Çiğdem Ay... more

COVİD-19’UN Anksi̇yete, Ölüm Korkusu Ve Obsesi̇f Kompulsi̇f Bozukluğuna Olan Etki̇si̇ni̇n İncelenmesi̇

Türkiye Bütüncül Psikoterapi Dergisi, Aug 23, 2022

Determining the relationship between high school students' perceived parental authority styles and self-esteem

Psychology Research on Education and Social Sciences, Jun 15, 2020

Karbamazepin tedavisi sırasında gelişen hiponatremi ve sonuçları: Bir olgu sunumu

Türkiye'de Psikiyatri Derg., 2006

Algılanan Stres Düzeyi ve Ruminasyon Arasındaki İlişkinin İncelenmesi Examination of the Relationship Between Perceived Stress Level And Rumination

Aydın İnsan ve Toplum Dergisi

Değerli okuyucu, Dergimizin 2022 Haziran sayısı ile sizlere bir kez daha ulaşmaktan mutluyuz. Bu ... more Değerli okuyucu, Dergimizin 2022 Haziran sayısı ile sizlere bir kez daha ulaşmaktan mutluyuz. Bu sayımızda da Psikoloji ve Sosyoloji çalışmalarından oluşan beş makale ile yanınızda olacağız. İlk makalemiz Rabia İslim DALBAŞI ve Cebrail KISA tarafından kaleme alınan ve algılanan stres düzeyi ile ruminasyon arasındaki ilişkiyi inceleyen bir derleme çalışmasıdır.

Investigation of anxiety and psychological well-being in adults during the Covid 19 pandemic period in Turkey

Olanzapin Kullanımına Bağlı Tardif Distoni Olgusu

Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2010

Olanzapin kullanımına bağlı tardif distoni olgusu Tardif distoni (TD) antipsikotik ajanlar tarafı... more Olanzapin kullanımına bağlı tardif distoni olgusu Tardif distoni (TD) antipsikotik ajanlar tarafından indüklenen, ekstremiteleri, gövdeyi ve yüz bölgesini etkileyen, bölgesel veya genel, devamlı, genellikle yavaş, istemsiz kıvrılma/bükülme hareketlerdir. Bir atipik antipsikotik olan olanzapinin klasik antipsikotiklere göre ekstrapiramidal yan etkilerinin daha az olduğu bilinmektedir. Bununla birlikte birçok vakada TD tedavisinde etkili olan olanzapinin bazı vakalarda da TD'ye neden olduğu bildirilmiştir. Bu yazıda 2 yıl olanzapin kullanan ve şizofreni tanısı olan bir hastada ortaya çıkan tardiv distoni olgusu ve sonrasındaki tedavi yaklaşımı sunuldu. Anah tar söz cük ler: Olanzapin, tardif distoni, atipik antipiskotiklere bağlı ekstrapiramidal yan etkiler Kli nik Psi ko far ma ko lo ji Bül te ni 2010;20:252-254 ABS TRACT: Olanzapine induced tardive dystonia: a case report Tardive dystonia (TD) is a movement disorder induced by antipsychotic agents, seen in extremities, face, and trunk. TD movements can be regional or generalized and are continuous and slow involuntary swirl or convolution movements. It is known that olanzapine as an atypical antipsychotic drug causes less extrapyramidal side effects than typical ones do. Furthermore it's recommended as treatment for TD cases caused by other antipsychotic treatments. On the other hand few olanzapine induced TD cases were reported in the literature. In this report, a tardive dystonia case developed in a schizophrenic patient, who was treated with olanzapine for two years and treatment approach after TD, was presented.

Analysis of the Relation Between Social Anxieties and Parental Attitudes of the Adolescent High School Students

In this study, the relation between social anxiety levels of adolescents and perceived parental a... more In this study, the relation between social anxiety levels of adolescents and perceived parental attitudes is aimed to be researched. This research was designed in accordance with correlational survey model which is one of the quantitative research models. Osmangazi district in city of Bursa was detected as the available universe of the research. Sample consists of 300 high-schoolers aged between 15-17 studying at Suleyman Celebi Anatolian High School. As data collection tools, “Socio-Demographical Information Form” to detect socio-demographical features, the “Social Anxiety Scale for Adolescents” (SAS-A) to measure social anxiety levels of the students, “Parental Attitude Scale” to measure perceived parental attitudes were used. . “Parental Attitude Scale” contains subtests of “Democratic Attitude”, “Protective Demanding Attitude”, “Authoritarian Attitude”. SAS-A consists of Fear of Negative Evaluation (FNE), Social Fear and Discomfort-General (SFD-General) and Social Fear and Disco...

Belirtiden Bozukluğa İstifleme

Hoarding is a psychological disorder characterized by excessive collecting, storage and inability... more Hoarding is a psychological disorder characterized by excessive collecting, storage and inability to discard large quantities of the objects, usually accompanying a severe level of distress or dysfunctionality. Despite the concept has been known for more than a century, it used to be conceptualized as a component of obsessive compulsive disorder. However, hoarding disorder appears as a distinct psychiatric disorder in the last updated version of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). Accordingly, in this review we aimed to make a general framework in understanding of hoarding disorder which is an attention-grabbing diagnosis in these days. In this regard, we addressed the etiology, clinical features of, and treatment approaches to hoarding disorder.

Long Term Follow-Up of PaƟ ents with Postpartum Psychosis

Results: Among the postpartum women, 73.9% developed psychosis during their first parturition. Th... more Results: Among the postpartum women, 73.9% developed psychosis during their first parturition. The postpartum psychosis and control groups were followed-up for 4.00 ± 1.62 (range: 2-6) and 3.96 ± 1.24 (range: 2-6) years, respectively. During the follow-up period, 21.7% of the postpartum patients developed a mood disorder, and 77.9% developed schizophrenia and other psychotic disorders. Among those in the control group, 32.0% were diagnosed with a mood disorder and 68.0% with schizophrenia and other psychotic disorders. The distribution of final diagnoses in the 2 groups were similar. Patients with postpartum psychosis experienced more confusion than the control subjects. During the follow-up period, 65.2% of the patients with postpartum psychosis and 72% of the control patients had recurrence. Conclusion: The course of postpartum psychosis was similar to DSM-IV diagnostic criteria, except for the presence of confusion. During the follow-up period, most of the patients in both groups...

Agranulocytosis induced with atypical antipsychotics: a case report

Bulletin of Clinical Psychopharmacology, 2001

Þizofreni Hastalarýnda Aile Ortamý ve Duygu Dýþavurumunun Deðerlendirilmesi

Assessment of anxiety disorders and related factors at the third trimester of pregnancy

Turkiye Aile Hekimligi Dergisi, 2009

Araflt›rma D o¤urganl›k dönemindeki kad›n, gebelik ve do-¤umla, önemli organik ve psikolojik de¤i... more Araflt›rma D o¤urganl›k dönemindeki kad›n, gebelik ve do-¤umla, önemli organik ve psikolojik de¤ifliklikler yaflar. Birçok çal›flma, do¤umun anksiyeteye yol açt›¤›n› göstermifltir. 1-3 Preterm do¤um ve düflük do¤um a¤›rl›¤›, do¤um öncesi depresyon ve/veya anksiyete ile iliflkili bulunmufltur. 4,5 Do¤um öncesi stresin; plasentay› ve annenin hipofiz-adrenal eksenini uyararak erken do-¤uma neden oldu¤u ileri sürülmektedir. 6 Erken do¤um ile plasentadan ve anneden kortikotropin hormonu sal›-n›m›n›n art›fl› iliflkili bulunmufltur. 6,7 Gebelikte, strese neden olan önemli bir faktör de be-be¤in sa¤l›k durumudur. Özellikle ilk hamilelikte, do-¤um süreci ve do¤um flekli ile ilgili kayg›lar s›k görülür. Baz› çal›flmalar, anksiyete ile gebelik komplikasyonlar›-Gebeli¤in son 3 ay›nda anksiyete bozuklu¤u ve iliflkili faktörlerin de¤erlendirilmesi

511 Comparison of local anaesthetic effects of lidocaine versus tramadol and the effect of child anxiety on pain level in circumcision procedure

European Urology Supplements, 2012

Şizofreni Tanılı Hastalarda Prolaktini Yükselten ve Az Etkileyen Antipsikotiklerin Prolaktin Seviyesi ve Kemik Mineral Yoğunluğu Üzerine Etkileri

Nöro Psikiyatri Arşivi, 2014

Introduction: We aimed to investigate the effects of antipsychotics on prolactin levels in patien... more Introduction: We aimed to investigate the effects of antipsychotics on prolactin levels in patients diagnosed with schizophrenia and the effects of hyperprolactinemia on bone mineral density (BMD) in patients on long-term antipsychotics. Method: In this study, we included eighty consecutive patients who were diagnosed with schizophrenia according to DSM-IV, had been using the same antipsychotic for the last ten months, and fulfilled the inclusion criteria. Data on sociodemographic characteristics of the patients were collected through an information sheet. The Scale for the Assessment of Negative Symptoms (SANS) and the Scale for the Assessment of Positive Symptoms (SAPS) were used to rate positive and negative symptoms of the patients. In addition, their body mass indices (BMI) were calculated. Prolactin levels were measured through luminescence immune assay and BMD measurements were made at lumbar and femoral sites using dual-energy x-ray absorbtiometry. Haloperidol (n=20) and risperidone (n=20) were assigned to prolactin-raising antipsychotic group, and olanzapine (n=20) and quetiapine (n=20) were assigned to prolactin-sparing antipsychotic group for this study. The effects of antipsychotics on BMD were compared among these groups. Results: Hyperprolactinemia was determined in 60% of haloperidol using patients, 90% of risperidone using patients, 25% of olanzapine using patients and 10% of quetiapine using patients. Mean prolactin levels were found to be significantly higher in prolactin-raising antipsychotic using group (p<0.001). There were no statistically significant differences in BMD values between the two groups, for the sites where the measurement was done. Lumbar spine and femoral neck T-scores and Z-scores in the prolactin-raising group significantly negatively correlated with the treatment durations and chlorpromazineequivalent doses (p<0.05). BMI and BMD values of both groups also displayed statistically significant positive correlations (p<0.05). Conclusion: The statistically significant differences in mean prolactin levels and numbers of patients with hyperprolactinemia between the treatment groups support the validity of classifying the antipsychotics as prolactin-raising and prolactin-sparing". The relationship of BMD with the treatment duration and doses in the prolactin-raising antipsychotic using group was deemed to be important, since it indicated that a decrease in BMD was to be expected in long-term antipsychotic treatment.

A comparison of symptom dimensions for obsessive compulsive disorder and obsessive compulsive-related disorders

PLOS ONE, 2019

In this study, it is aimed to determine obsessive compulsive-related disorders (OCRDs) comorbidit... more In this study, it is aimed to determine obsessive compulsive-related disorders (OCRDs) comorbidity among the patients with obsessive compulsive disorder (OCD) and compare patients with OCD with or without comorbid OCRDs in terms of the severity of their OCD symptoms, symptom dimensions, and comorbidity with other axis I disorders. The study included 90 patients diagnosed as having OCD according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR). The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) diagnostic criteria for OCRDs were used to determine the presence of OCRDs. In order to determine the symptom dimensions and severity of these individuals' OCD symptoms, we administered the Dimensional Obsessive Compulsive Scale (DOCS) and The Yale-Brown Obsessive Compulsive Scale (Y-BOCS). In our study, 20% of the patients with OCD simultaneously met the criteria for at least one OCRD, we also found that a significantly greater proportion of this group were men. None of the mentioned disorders was associated with any symptom dimensions we evaluated using DOCS. In addition, no differences were found in the severity of OCD symptoms and comorbid axis I disorders between the group with comorbid OCRDs and the group without comorbid OCRDs. There was no significant relationship between the symptom dimensions of OCD and OCRDs. It is found that OCRD comorbidity does not increase the severity of OCD symptoms and the prevalence of an axis I diagnosis.

Farkli Kategori̇de Yarişan Taekwondocularin Spor Yaralanmalarina Karşi, Kaygi Durumlarinin İncelenmesi̇

The Online Journal of Recreation and Sport

This study aims to examine the sports injury anxiety levels of taekwondo players, which is a psyc... more This study aims to examine the sports injury anxiety levels of taekwondo players, which is a psychological factor that causes injury and negatively affects athletes apart from some physical strategies in the prevention of injuries. A total of 617 (326 men and 291 women) taekwondo players actively engaged in sports from different competition categories participated in the study.

Karbamazepin Tedavisi Sırasında Gelişen Hiponatremi Ve Sonuçları: Bir Olgu Sunumu

Klozapin tedavisini pimozid ile güçlendirme yaklaşımı: Tedaviye dirençli bir şizofreni olgusu

Noropsikiyatri Arsivi-archives of Neuropsychiatry, 2010

Page 1. Hatice ALKAN AKDA⁄, Cebrail KISA, Gülcan BEKK‹, Erol GÖKA Numune Hastanesi 1. Psikiyatri ... more

The effects of prolactin-raising and prolactin-sparing antipsychotics on prolactin levels and bone mineral density in schizophrenic patients/Sizofreni tanili hastalarda prolaktini yukselten ve az etkileyen antipsikotiklerin prolaktin seviyesi ve kemik mineral yogunlugu uzerine etkileri

Archives of Neuropsychiatry, Sep 1, 2014

Hekimlerin Konversiyon Bozukluğuna Yaklaşımını Etkileyen Faktörler

Klinik Psikiyatri …, 2004

Page 1. Hekimlerin Konversiyon Bozukluğuna Yaklaşımını Etkileyen Faktörler Uğur Bediz1, Çiğdem Ay... more

COVİD-19’UN Anksi̇yete, Ölüm Korkusu Ve Obsesi̇f Kompulsi̇f Bozukluğuna Olan Etki̇si̇ni̇n İncelenmesi̇

Türkiye Bütüncül Psikoterapi Dergisi, Aug 23, 2022

Determining the relationship between high school students' perceived parental authority styles and self-esteem

Psychology Research on Education and Social Sciences, Jun 15, 2020

Karbamazepin tedavisi sırasında gelişen hiponatremi ve sonuçları: Bir olgu sunumu

Türkiye'de Psikiyatri Derg., 2006

Algılanan Stres Düzeyi ve Ruminasyon Arasındaki İlişkinin İncelenmesi Examination of the Relationship Between Perceived Stress Level And Rumination

Aydın İnsan ve Toplum Dergisi

Değerli okuyucu, Dergimizin 2022 Haziran sayısı ile sizlere bir kez daha ulaşmaktan mutluyuz. Bu ... more Değerli okuyucu, Dergimizin 2022 Haziran sayısı ile sizlere bir kez daha ulaşmaktan mutluyuz. Bu sayımızda da Psikoloji ve Sosyoloji çalışmalarından oluşan beş makale ile yanınızda olacağız. İlk makalemiz Rabia İslim DALBAŞI ve Cebrail KISA tarafından kaleme alınan ve algılanan stres düzeyi ile ruminasyon arasındaki ilişkiyi inceleyen bir derleme çalışmasıdır.

Investigation of anxiety and psychological well-being in adults during the Covid 19 pandemic period in Turkey

Olanzapin Kullanımına Bağlı Tardif Distoni Olgusu

Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2010

Olanzapin kullanımına bağlı tardif distoni olgusu Tardif distoni (TD) antipsikotik ajanlar tarafı... more Olanzapin kullanımına bağlı tardif distoni olgusu Tardif distoni (TD) antipsikotik ajanlar tarafından indüklenen, ekstremiteleri, gövdeyi ve yüz bölgesini etkileyen, bölgesel veya genel, devamlı, genellikle yavaş, istemsiz kıvrılma/bükülme hareketlerdir. Bir atipik antipsikotik olan olanzapinin klasik antipsikotiklere göre ekstrapiramidal yan etkilerinin daha az olduğu bilinmektedir. Bununla birlikte birçok vakada TD tedavisinde etkili olan olanzapinin bazı vakalarda da TD'ye neden olduğu bildirilmiştir. Bu yazıda 2 yıl olanzapin kullanan ve şizofreni tanısı olan bir hastada ortaya çıkan tardiv distoni olgusu ve sonrasındaki tedavi yaklaşımı sunuldu. Anah tar söz cük ler: Olanzapin, tardif distoni, atipik antipiskotiklere bağlı ekstrapiramidal yan etkiler Kli nik Psi ko far ma ko lo ji Bül te ni 2010;20:252-254 ABS TRACT: Olanzapine induced tardive dystonia: a case report Tardive dystonia (TD) is a movement disorder induced by antipsychotic agents, seen in extremities, face, and trunk. TD movements can be regional or generalized and are continuous and slow involuntary swirl or convolution movements. It is known that olanzapine as an atypical antipsychotic drug causes less extrapyramidal side effects than typical ones do. Furthermore it's recommended as treatment for TD cases caused by other antipsychotic treatments. On the other hand few olanzapine induced TD cases were reported in the literature. In this report, a tardive dystonia case developed in a schizophrenic patient, who was treated with olanzapine for two years and treatment approach after TD, was presented.

Analysis of the Relation Between Social Anxieties and Parental Attitudes of the Adolescent High School Students

In this study, the relation between social anxiety levels of adolescents and perceived parental a... more In this study, the relation between social anxiety levels of adolescents and perceived parental attitudes is aimed to be researched. This research was designed in accordance with correlational survey model which is one of the quantitative research models. Osmangazi district in city of Bursa was detected as the available universe of the research. Sample consists of 300 high-schoolers aged between 15-17 studying at Suleyman Celebi Anatolian High School. As data collection tools, “Socio-Demographical Information Form” to detect socio-demographical features, the “Social Anxiety Scale for Adolescents” (SAS-A) to measure social anxiety levels of the students, “Parental Attitude Scale” to measure perceived parental attitudes were used. . “Parental Attitude Scale” contains subtests of “Democratic Attitude”, “Protective Demanding Attitude”, “Authoritarian Attitude”. SAS-A consists of Fear of Negative Evaluation (FNE), Social Fear and Discomfort-General (SFD-General) and Social Fear and Disco...

Belirtiden Bozukluğa İstifleme

Hoarding is a psychological disorder characterized by excessive collecting, storage and inability... more Hoarding is a psychological disorder characterized by excessive collecting, storage and inability to discard large quantities of the objects, usually accompanying a severe level of distress or dysfunctionality. Despite the concept has been known for more than a century, it used to be conceptualized as a component of obsessive compulsive disorder. However, hoarding disorder appears as a distinct psychiatric disorder in the last updated version of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). Accordingly, in this review we aimed to make a general framework in understanding of hoarding disorder which is an attention-grabbing diagnosis in these days. In this regard, we addressed the etiology, clinical features of, and treatment approaches to hoarding disorder.

Long Term Follow-Up of PaƟ ents with Postpartum Psychosis

Results: Among the postpartum women, 73.9% developed psychosis during their first parturition. Th... more Results: Among the postpartum women, 73.9% developed psychosis during their first parturition. The postpartum psychosis and control groups were followed-up for 4.00 ± 1.62 (range: 2-6) and 3.96 ± 1.24 (range: 2-6) years, respectively. During the follow-up period, 21.7% of the postpartum patients developed a mood disorder, and 77.9% developed schizophrenia and other psychotic disorders. Among those in the control group, 32.0% were diagnosed with a mood disorder and 68.0% with schizophrenia and other psychotic disorders. The distribution of final diagnoses in the 2 groups were similar. Patients with postpartum psychosis experienced more confusion than the control subjects. During the follow-up period, 65.2% of the patients with postpartum psychosis and 72% of the control patients had recurrence. Conclusion: The course of postpartum psychosis was similar to DSM-IV diagnostic criteria, except for the presence of confusion. During the follow-up period, most of the patients in both groups...

Agranulocytosis induced with atypical antipsychotics: a case report

Bulletin of Clinical Psychopharmacology, 2001

Þizofreni Hastalarýnda Aile Ortamý ve Duygu Dýþavurumunun Deðerlendirilmesi

Assessment of anxiety disorders and related factors at the third trimester of pregnancy

Turkiye Aile Hekimligi Dergisi, 2009

Araflt›rma D o¤urganl›k dönemindeki kad›n, gebelik ve do-¤umla, önemli organik ve psikolojik de¤i... more Araflt›rma D o¤urganl›k dönemindeki kad›n, gebelik ve do-¤umla, önemli organik ve psikolojik de¤ifliklikler yaflar. Birçok çal›flma, do¤umun anksiyeteye yol açt›¤›n› göstermifltir. 1-3 Preterm do¤um ve düflük do¤um a¤›rl›¤›, do¤um öncesi depresyon ve/veya anksiyete ile iliflkili bulunmufltur. 4,5 Do¤um öncesi stresin; plasentay› ve annenin hipofiz-adrenal eksenini uyararak erken do-¤uma neden oldu¤u ileri sürülmektedir. 6 Erken do¤um ile plasentadan ve anneden kortikotropin hormonu sal›-n›m›n›n art›fl› iliflkili bulunmufltur. 6,7 Gebelikte, strese neden olan önemli bir faktör de be-be¤in sa¤l›k durumudur. Özellikle ilk hamilelikte, do-¤um süreci ve do¤um flekli ile ilgili kayg›lar s›k görülür. Baz› çal›flmalar, anksiyete ile gebelik komplikasyonlar›-Gebeli¤in son 3 ay›nda anksiyete bozuklu¤u ve iliflkili faktörlerin de¤erlendirilmesi

511 Comparison of local anaesthetic effects of lidocaine versus tramadol and the effect of child anxiety on pain level in circumcision procedure

European Urology Supplements, 2012

Şizofreni Tanılı Hastalarda Prolaktini Yükselten ve Az Etkileyen Antipsikotiklerin Prolaktin Seviyesi ve Kemik Mineral Yoğunluğu Üzerine Etkileri

Nöro Psikiyatri Arşivi, 2014

Introduction: We aimed to investigate the effects of antipsychotics on prolactin levels in patien... more Introduction: We aimed to investigate the effects of antipsychotics on prolactin levels in patients diagnosed with schizophrenia and the effects of hyperprolactinemia on bone mineral density (BMD) in patients on long-term antipsychotics. Method: In this study, we included eighty consecutive patients who were diagnosed with schizophrenia according to DSM-IV, had been using the same antipsychotic for the last ten months, and fulfilled the inclusion criteria. Data on sociodemographic characteristics of the patients were collected through an information sheet. The Scale for the Assessment of Negative Symptoms (SANS) and the Scale for the Assessment of Positive Symptoms (SAPS) were used to rate positive and negative symptoms of the patients. In addition, their body mass indices (BMI) were calculated. Prolactin levels were measured through luminescence immune assay and BMD measurements were made at lumbar and femoral sites using dual-energy x-ray absorbtiometry. Haloperidol (n=20) and risperidone (n=20) were assigned to prolactin-raising antipsychotic group, and olanzapine (n=20) and quetiapine (n=20) were assigned to prolactin-sparing antipsychotic group for this study. The effects of antipsychotics on BMD were compared among these groups. Results: Hyperprolactinemia was determined in 60% of haloperidol using patients, 90% of risperidone using patients, 25% of olanzapine using patients and 10% of quetiapine using patients. Mean prolactin levels were found to be significantly higher in prolactin-raising antipsychotic using group (p<0.001). There were no statistically significant differences in BMD values between the two groups, for the sites where the measurement was done. Lumbar spine and femoral neck T-scores and Z-scores in the prolactin-raising group significantly negatively correlated with the treatment durations and chlorpromazineequivalent doses (p<0.05). BMI and BMD values of both groups also displayed statistically significant positive correlations (p<0.05). Conclusion: The statistically significant differences in mean prolactin levels and numbers of patients with hyperprolactinemia between the treatment groups support the validity of classifying the antipsychotics as prolactin-raising and prolactin-sparing". The relationship of BMD with the treatment duration and doses in the prolactin-raising antipsychotic using group was deemed to be important, since it indicated that a decrease in BMD was to be expected in long-term antipsychotic treatment.