Academia.edu no longer supports Internet Explorer.
To browse Academia.edu and the wider internet faster and more securely, please take a few seconds to upgrade your browser.
Related Authors
Amity University
Manipal Academy of Higher Education
Texas A&M University
University of Cagliari
CSIC (Consejo Superior de Investigaciones Científicas-Spanish National Research Council)
Moscow State University
Gazi University
University of California, San Diego
Stanford University
University of Illinois at Urbana-Champaign
Uploads
Papers by Kishor Sarkar
molecule onto chitosan backbone through naphthalimide moiety by simple substitution reaction. 4-
Bromo-1,8-naphthalic anhydride was used as fluorescent probe due to its strong fluorescence and good
photo-stability property and the presence of a fine tunable bromide functional group in the naphthalimide
ring, in this work. The copolymer was characterized by FTIR, elemental analysis and XRD. The
fluorescence property of the copolymer was determined by UV–vis spectrometer and spectrofluorometer.
The effects of pH and temperature on fluorescence property of the copolymer were also studied.
The graft copolymer with degree of substitution 37.6 of PEI onto chitosan showed better complexation
ability with DNA at comparatively low N/P (nitrogen to phosphate ratio) ratio 1.0 compared to that of
chitosan (N/P ratio 2.0). The cytotoxicity of PEI largely decreased after grafting with chitosan and all the
copolymers showed above 50% cell viability even at high polymer concentration (300 g/mL). Therefore,
the prepared fluorescent chitosan-graft-PEI copolymer may be used as a biological marker as well as drug
or gene carrier with low toxicity.
molecule onto chitosan backbone through naphthalimide moiety by simple substitution reaction. 4-
Bromo-1,8-naphthalic anhydride was used as fluorescent probe due to its strong fluorescence and good
photo-stability property and the presence of a fine tunable bromide functional group in the naphthalimide
ring, in this work. The copolymer was characterized by FTIR, elemental analysis and XRD. The
fluorescence property of the copolymer was determined by UV–vis spectrometer and spectrofluorometer.
The effects of pH and temperature on fluorescence property of the copolymer were also studied.
The graft copolymer with degree of substitution 37.6 of PEI onto chitosan showed better complexation
ability with DNA at comparatively low N/P (nitrogen to phosphate ratio) ratio 1.0 compared to that of
chitosan (N/P ratio 2.0). The cytotoxicity of PEI largely decreased after grafting with chitosan and all the
copolymers showed above 50% cell viability even at high polymer concentration (300 g/mL). Therefore,
the prepared fluorescent chitosan-graft-PEI copolymer may be used as a biological marker as well as drug
or gene carrier with low toxicity.
molecule onto chitosan backbone through naphthalimide moiety by simple substitution reaction. 4-
Bromo-1,8-naphthalic anhydride was used as fluorescent probe due to its strong fluorescence and good
photo-stability property and the presence of a fine tunable bromide functional group in the naphthalimide
ring, in this work. The copolymer was characterized by FTIR, elemental analysis and XRD. The
fluorescence property of the copolymer was determined by UV–vis spectrometer and spectrofluorometer.
The effects of pH and temperature on fluorescence property of the copolymer were also studied.
The graft copolymer with degree of substitution 37.6 of PEI onto chitosan showed better complexation
ability with DNA at comparatively low N/P (nitrogen to phosphate ratio) ratio 1.0 compared to that of
chitosan (N/P ratio 2.0). The cytotoxicity of PEI largely decreased after grafting with chitosan and all the
copolymers showed above 50% cell viability even at high polymer concentration (300 g/mL). Therefore,
the prepared fluorescent chitosan-graft-PEI copolymer may be used as a biological marker as well as drug
or gene carrier with low toxicity.
molecule onto chitosan backbone through naphthalimide moiety by simple substitution reaction. 4-
Bromo-1,8-naphthalic anhydride was used as fluorescent probe due to its strong fluorescence and good
photo-stability property and the presence of a fine tunable bromide functional group in the naphthalimide
ring, in this work. The copolymer was characterized by FTIR, elemental analysis and XRD. The
fluorescence property of the copolymer was determined by UV–vis spectrometer and spectrofluorometer.
The effects of pH and temperature on fluorescence property of the copolymer were also studied.
The graft copolymer with degree of substitution 37.6 of PEI onto chitosan showed better complexation
ability with DNA at comparatively low N/P (nitrogen to phosphate ratio) ratio 1.0 compared to that of
chitosan (N/P ratio 2.0). The cytotoxicity of PEI largely decreased after grafting with chitosan and all the
copolymers showed above 50% cell viability even at high polymer concentration (300 g/mL). Therefore,
the prepared fluorescent chitosan-graft-PEI copolymer may be used as a biological marker as well as drug
or gene carrier with low toxicity.